Monday, 30 April 2018
In a world-first study , researchers at The University of Western Australia will examine the effect medicinal cannabi s has on adults suffering from chronic insomnia.
Around one in three Australians has regular difficulty getting to sleep or staying asleep and it is believed the sedation effect brought on by medicinal cannabis could be an alternative treatment for those experiencing the condition .
The study will be coordinated through the UWA Centre for Sleep Science using a cannabinoid extract provided by Zelda Therapeu a tics , an Australian medical research and development company.
UWA Study lead Professor Peter Eastwood said current evidence suggest ed medicinal cannabis could be a less invasive alternative to current drugs on the market.
“Pr escription medicines such as benzodiazepines ( e.g. Temazepam), non-benzodiazepine hypnotics ( e.g. Stilnox, Sonata, Imovane) and some antidepressants and antihistamines can have unpleasant side effects and when used long-term can result in depe ndence and withdrawal symptoms,” Professor Eastwood said.
“ Based on previous research we believe a small dose of medicinal cannabinoid may be effective for treating chronic insomnia and have fewer side effects than current drug treatment options.”
The study involves participants taking either a medicinal cannabinoid for two weeks or a ‘place bo’ with no active ingredients and then completing a series of assessments and questionnaires relating to how they slept .
T he participant s will then crossover the medications for another two weeks and return again for the same assessments. The y won’t know the order in which they receive the ‘active’ or ‘placebo’ medication.
The medication is in an oil formulation which is administered through a dropper under the tong ue one hour before going to bed . The quality of sleep is then measured with a wrist-based activity monitor as well a s three overnight sleeps in the sleep centre.
“ The use of medicinal cannabis for treating conditions such as epilepsy and chronic pain is reasonably well documented, however its use for treating insom nia is considered experimental,” Professor Eastwood said.
Zelda Therapeutics E xecut ive C hairman Harry Karelis said it ha d been a very rigorous process but they were now well positioned to undertake a clinical trial of this nature in Australia .
“We are very pleased to have partnered with the leading researchers in this field and the prestigious UWA Centre for Sleep Science, and are confident this clinical trial will deliver the high-quality data we need to further develop and commercialise our medicinal cannabis formulation,” Mr Karelis said.
David Stacey (UWA Media and Public Relations Manager) (+61 8) 6488 3229 / (+61 4) 32 637 716
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